The PLUS against diarrhea

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Vitaplus® Boulardii combines 500 mg of a probiotic yeast called Saccharomyces boulardii CNCM I-3799, with 1x1010 of the lactic bacteria: Lactobacillus rhamnosus GG (ATCC 53103) and 500 mg of fructooligosaccharides (FOS-Actilight®)

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CN: 177214.5

Vitaplus® Boulardii contains the 2 probiotic strains most studied and most recommended by the ESPGHAN(1) and WGO(2) in:
  • Antibiotic Associated Diarrhea
  • Traveler's Diarrhea
  • Acute Gastroenteritis
  • Bacterial or viral diarrhea (caused by rotavirus in infants).
  • Diarrhea of non-specific origin
  • Prevention of recurrent infection associated with Clostridium difficile.
  • Candida associated to antibiotic
  • H.pylori infection

Vitaplus® boulardii combines, on the one hand, two types of microorganisms, the probiotic yeast Saccharomyces cerevisiae var. boulardii CNCM I-3799 500 mg and the lactic acid bacteria Lactobacillus rhamnosus GG (ATCC 53103) 1×1010 CFU*, and, on the other hand, the benefits of fructooligosaccharides (FOS-Actilight®) 500 mg.

This symbiotic combination helps to restore the balance of the intestinal microbiota in those situations where it may have been altered.

Saccharomyces boulardii and Lactobacillus rhamnosus GG are the 2 most studied strains with the most evidence according to the international guidelines ESPGHAN(1) and WGO(2).

Saccharomyces boulardii and Lactobacillus rhamnosus GG are considered with a strong recommendation level in case of Antibiotic Associated Diarrhea Prevention(2) and are recommended together with oral rehydration therapy in Acute Diarrhea in children(1).

Fructooligosaccharides (FOS-Actilight®) are a type of soluble fiber with prebiotic properties, stimulating the normal microbiota and helping to maintain a healthy digestive system. The prebiotic effect of FOS-Actilight® has been demonstrated in more than 50 human clinical studies.

*Colony Forming Units

The recommended dose is 1–2 sticks a day, just before or during any of the meals. The product is designed to be ingested directly. It is not necessary to mix it with food or dilute it in water; although if preferred, it can be taken diluted or combined with other foods, such as: juices, smoothies, yogurts, etc.

Vitaplus® Boulardii is compatible with antibiotics intake. It can be administered to children from 3 years of age.

Usage recommendations:

  • In adults:
    • Adjuvant treatment of H. pylori treatment: 1–2 sticks during the whole treatment with antibiotics.
    • Prevention of recurrent infection associated with C. difficile: 1–2 sticks a day, for 4 weeks.
    • Acute diarrhea (AD): 1 stick twice a day, for 5–7 days.
    • Traveler’s Diarrhea: 1 stick per day (start 3 days before departure and continue during the trip)
  • In children:
    • Prevention of antibiotic-associated diarrhea (AAD): 1 stick per day, for 10 days.
    • Treatment of acute gastroenteritis: 1–2 sticks a day, for 5–7 days.

10 comfortable milk flavoured orodispersible sticks.



Intestinal dysbiosis is an important imbalance of the intestinal microbiota. These changes in the concentration of intestinal bacteria can contribute to the development or worsening of many disorders or chronic intestinal degenerative diseases: acute diarrhea, diarrhea associated or not with antibiotics, traveler’s diarrhea, inflammatory bowel disease or irritable bowel syndrome (IBS) , ulcerative colitis, Crohn’s disease, pouchitis, Clostridium difficile infection.

VitaPLUS® Boulardii is a food supplement with symbiotic action (combining probiotics and prebiotics), which favors the survival and implantation of probiotics, therefore its activity in the gastrointestinal tract, and growth against potentially pathogenic microorganisms.

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